Pathophysiology of Age-Related Hearing Loss (Peripheral and Central)
Kyu-Yup Lee
Korean J Audiol. 2013;17(2):45-49.   Published online 2013 Sep 24     DOI:
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Life.2021; 11(10): 1102.     CrossRef
Cochlear Inflammaging in Relation to Ion Channels and Mitochondrial Functions
Parveen Bazard, Jennifer Pineros, Robert D. Frisina, Mark A. Bauer, Alejandro A. Acosta, Lauren R. Paganella, Dominika Borakiewicz, Mark Thivierge, Freyda L. Mannering, Xiaoxia Zhu, Bo Ding
Cells.2021; 10(10): 2761.     CrossRef
Speech intelligibility enhancement in elderly with high-frequency hearing loss through visual speech perception
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Journal of Hypertension.2016; 34(4): 736.     CrossRef
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Aging.2016; 8(4): 730.     CrossRef
Relationships among hearing loss, cognition and balance ability in community-dwelling older adults
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Hypertension and cochlear hearing loss
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Age-related hearing impairment and the triad of acquired hearing loss
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Age-related changes in mitochondrial antioxidant enzyme Trx2 and TXNIP-Trx2-ASK1 signal pathways in the auditory cortex of a mimetic aging rat model: changes to Trx2 in the auditory cortex
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FEBS Journal.2015; 282(14): 2758.     CrossRef